Conformation dependence of DNA electrophoretic mobility in a converging channel

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Conformation dependence of DNA electrophoretic mobility in a converging channel.

The electrophoresis of lambda-DNA is observed in a microscale converging channel where the center-of-masses trajectories of DNA molecules are tracked to measure instantaneous electrophoretic (EP) mobilities of DNA molecules of various stretch lengths and conformations. Contrary to the usual assumption that DNA mobility is a constant, independent of field and DNA length in free solution, we find...

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ژورنال

عنوان ژورنال: ELECTROPHORESIS

سال: 2010

ISSN: 0173-0835

DOI: 10.1002/elps.201000081